結構不同、側重點不同、適用語境不同。be full of是主動結構，be filled with被動結構。be full of更強調狀態，尤其強調“滿滿的”狀態；be filled with更強調動態的過程。當表示某種事物的程度為“非常”的時候，只能用be full of。

be full of的例句

The room is full of people.

房間里擠滿了人。

The bottle is full of water.

瓶子里裝滿了水。

The students here are full of energy.

這里的學生們精力充沛。

be filled with的例句

I want my life to be filled with happiness.

我想要我的生活充滿快樂。

Besides the name of each candidate, there was a box to be filled with a number.

每個候選人名字旁邊都有一個有待裝選票的盒子。

If you approach each of your challenges with creativity then your life will be filled with adventures.

如果你創造性地靠近這些挑戰你的生活將充滿了冒險。